MONAI through 1.6.0 PersistentDataset Remote Code Execution via Pickle Cache (CVE-2026-100841) | HOL Guard CVE

High · CVSS 8.5CVE-2026-100841

MONAI through 1.6.0 PersistentDataset Remote Code Execution via Pickle Cache

Answer in brief

CVE-2026-100841 records a High severity (CVSS 8.5) vulnerability in MONAI through 1.6.0 PersistentDataset Remote Code Execution via Pickle Cache. The current sources do not mark it as known exploited. The current feed maps Project-MONAI/MONAI (generic), Project-MONAI/MONAI (generic). Check affected ranges and fixed versions before updating.

Analysis pending evidence review

HOL Guard separates source facts from reviewed analysis. See the methodology.

Published Sep 27, 2026Updated Sep 27, 2026Source checked Sep 27, 2026First seen by HOL Sep 27, 2026Material review Sep 27, 2026

Upstream Advisory

Key facts

Risk: High · CVSS 8.5
Exploitation: Not marked as known exploited
Affected software: 2 mapped packages or products
Fix availability: Not reported

Why this deserves its current priority

CVSS is 8.5. The current sources do not mark it as known exploited. Treat this as a source-backed prioritization signal, not a statement about your environment.

Analysis status

Analysis pending evidence review

Factual feed record only; HOL analysis is not approved for indexing. Read the methodology.

Affected scope and exposure questions

The current feed maps Project-MONAI/MONAI (generic), Project-MONAI/MONAI (generic). Check affected ranges and fixed versions before updating.

Mapped affected packages and fixed versions
Package	Affected range	Fixed version
Project-MONAI/MONAIgeneric	1.6.0	Not reported
Project-MONAI/MONAIgeneric	>=0 <=1.6.0	Not reported

Recommended response

Check inventory. Check lockfiles and deployed manifests for Project-MONAI/MONAI, Project-MONAI/MONAI.
Review the reported fix. Monitor this advisory for an available fix and review any installs of the affected package.

Evidence timeline and material changes

Published upstream
Sep 27, 2026
Evidence: source:cvelist:source_dates:source-dates:record
Source modified
Sep 27, 2026
Evidence: source:cvelist:source_dates:source-dates:record
First seen by HOL
Sep 27, 2026

Sources and claim methodology

Upstream source description

In MONAI 1.6.0, PersistentDataset (monai/data/dataset.py) explicitly rejects the combination track_meta=True with weights_only=True, forcing users who cache MetaTensors (the default tensor type in MONAI >= 1.0) to run torch.load(hashfile, weights_only=False). Related cache helpers in monai/data/utils.py also call pickle.loads on cached content and derive cache keys with hashlib.md5. As a result, a local user with write access to a shared or world-writable cache_dir (e.g. /tmp/monai_cache, HPC scratch, ~/.cache/monai) can place a malicious pickle file that is deserialized the next time another user's MONAI pipeline reads the cache, resulting in arbitrary code execution in that user's context. All released versions of the monai pip package are affected; no patched version is available as of the advisory.

Quoted source text, attributed separately from HOL analysis.