HOL LogoGuard

Explore HOL

  • HOL home
  • AI agent registry
  • AI plugins
  • Open standards
  • HOL members
  • Sponsor HOL
  • Advertise with HOL

Guard product

  • Guard overviewLocal security and control for AI agents and the tools they use.
  • FeaturesRuntime protection, policy routing, review, and evidence.

Explore Guard

  • Product previewWalk through Guard surfaces in read-only demo mode.
  • ComparisonCompare Guard with native controls and AI security vendors.

AI tools

  • All AI toolsEvery supported AI tool and how Guard applies policy to it.
  • Codex
  • Claude Code
  • Cursor
  • Antigravity CLI
  • OpenCode
  • Hermes
  • OpenClaw
  • GitHub Copilot CLI
  • Antigravity
  • Kimi
  • Grok
  • Pi / Oh My Pi
  • Zcode

Extensions

  • All extensionsBrowse command and MCP coverage with owners and stated limits.
  • Command coverageShell command protection across clouds, databases, backups, and packages.
  • MCP server coverageSee how Guard maps risk state across MCP tools and servers.
  • Core safetyThe safety floor listings that ship with Guard.
  • Data and resilienceBackup and storage command protection.
  • Cloud and infrastructureAWS, Azure, GCP, Kubernetes, and more.

Security

  • AI security hubSecurity research, advisories, and agent safety coverage.
  • AI tool securitySecurity profiles for each supported coding agent.
  • Safe labsHands-on attack simulations with safe boundaries.
  • Redacted warningsReal blocked actions with sensitive details removed.
  • AdvisoriesCoordinated disclosure reports for AI tooling.
  • Active CVEsSearch active CVEs affecting AI tooling.

Learn

  • Security guidesPractical guides for securing AI agent workflows.
  • DocsInstall, configure, and operate Guard with confidence.
  • ResearchPublished security research, benchmarks, and methodology.

Community

  • ReleasesVersion history, shipped changes and upgrade notes.
  • ContributorsThe people and contributions behind HOL Guard.
  • AffiliatesShare Guard with your audience and earn from referrals.
  • SponsorFund agreed research, implementation and shared testing through the HOL Partner Program.
  • AdvertiseCompare README logo placements, previews and monthly prices, or promote a plugin or extension.
PricingEnterpriseOpen AppInstall Guard
  1. Guard
  2. Security
  3. CVEs
  4. CVE 2026 17583 thermo fisher applied biosystems genetic
HOL Guard

Public security guidance for teams protecting AI harnesses, MCP servers, skills, prompts, and local tool execution.

Install Guard

AI Security

  • Prompt injection
  • MCP security
  • OWASP MCP mapping
  • Supply chain

Resources

  • Trust packet
  • Harness setup
  • Redacted warnings
  • Safe labs

Product

  • Install Guard
  • Pricing
  • Open dashboard
Guard
  • Guard Overview
  • Releases
  • Contributors
  • Install Guard
  • Pricing
Docs
  • Documentation Index
  • Developer Hub
  • API Reference
  • Root OpenAPI
  • Registry OpenAPI
  • Run in Postman
  • Standards
  • Submit ERC-8004 Contract
  • Feature Your Agent
Best Plugins
  • Browse Plugins
  • Plugin Launches
  • Best Claude Plugins
  • Best Codex Plugins
  • Best Grok Plugins
  • Best Kimi Plugins
  • Best DeepSeek Plugins
  • Best Antigravity Plugins
  • Best MCP Servers
  • Best Cursor Plugins
  • Best OpenCode Plugins
Best Agents
  • Best ERC-8004 Agents
  • Best Virtuals Agents
  • Best MCP Servers
  • Best A2A Agents
  • Best x402 Payable
  • All Categories
Community
  • Contribute to HOL
  • Telegram
  • X
More
  • About HOL
  • Sponsor
  • Advertise
  • Affiliate program
  • Contact
  • Blog
  • GitHub
  • Privacy
  • Terms of Service
Settings

Copyright © 2026 HOL DAO LLC. All rights reserved.

Back to active CVEs
High · CVSS 8.3CVE-2026-17583

Thermo Fisher Applied Biosystems Genetic Analyzers Missing Support for Integrity CheckCVE-2026-17583

Answer in brief

CVE-2026-17583 records a High severity (CVSS 8.3) vulnerability in Thermo Fisher Applied Biosystems Genetic Analyzers Missing Support for Integrity Check. The current sources do not mark it as known exploited. The current feed maps Thermo Fisher/ABI PRISM 3100/3100-Avant Data Collection Software (generic), Thermo Fisher/ABI PRISM 3100/3100-Avant Data Collection Software (generic), Thermo Fisher/ABI PRISM 310 Data Collection Software (generic), Thermo Fisher/ABI PRISM 310 Data Collection Software (generic) and additional mapped packages. Check affected ranges and fixed versions before updating.

Analysis pending evidence review

HOL Guard separates source facts from reviewed analysis. See the methodology.

Published Aug 5, 2026Updated Aug 26, 2026Source checked Nov 4, 2026First seen by HOL Aug 5, 2026Material review Aug 26, 2026
Upstream Advisory

Record context

Vulnerability class
Vulnerability
EPSS
Not reported
CWE IDs
CWE-353
Source
CVE List V5
Source checked
Nov 4, 2026
References
3 linked sources
Open source record

Key facts

Risk
High · CVSS 8.3
Exploitation
Not marked as known exploited
Affected software
24 mapped packages or products
Fix availability
Not reported

Why this deserves its current priority

CVSS is 8.3. The current sources do not mark it as known exploited. Treat this as a source-backed prioritization signal, not a statement about your environment.

Analysis status

Analysis pending evidence review

Factual feed record only; HOL analysis is not approved for indexing. Read the methodology.

Affected scope and exposure questions

The current feed maps Thermo Fisher/ABI PRISM 3100/3100-Avant Data Collection Software (generic), Thermo Fisher/ABI PRISM 3100/3100-Avant Data Collection Software (generic), Thermo Fisher/ABI PRISM 310 Data Collection Software (generic), Thermo Fisher/ABI PRISM 310 Data Collection Software (generic) and additional mapped packages. Check affected ranges and fixed versions before updating.

Affected products and reported versions
ProductAffected versionsFixed versions
cpe:2.3:a:thermofisher:abi_prism_3100\/3100-avant_data_collection_software:*:*:*:*:*:*:*:*Not reportedNot reported
cpe:2.3:a:thermofisher:abi_prism_310_data_collection_software:*:*:*:*:*:*:*:*Not reportedNot reported
cpe:2.3:a:thermofisher:applied_biosystems_3130_series_data_collection_software:*:*:*:*:*:*:*:*Not reportedNot reported
cpe:2.3:a:thermofisher:applied_biosystems_3500\/3500xl_series_data_collection_software:*:*:*:*:*:*:*:*Not reportedNot reported
cpe:2.3:a:thermofisher:applied_biosystems_3730\/3730xl_series_data_collection_software:*:*:*:*:*:*:*:*Not reportedNot reported
cpe:2.3:a:thermofisher:applied_biosystems_seqstudio_flex_series_instrument_software:*:*:*:*:*:*:*:*Not reportedNot reported
cpe:2.3:a:thermofisher:applied_biosystems_seqstudio_genetic_analyzer_data_collection_software:*:*:*:*:*:*:*:*Not reportedNot reported
cpe:2.3:a:thermofisher:genemapper_id-x:*:*:*:*:*:*:*:*Not reportedNot reported
Mapped affected packages and fixed versions
PackageAffected rangeFixed version
Thermo Fisher/ABI PRISM 3100/3100-Avant Data Collection Softwaregeneric>=0 <=2.0Not reported
Thermo Fisher/ABI PRISM 3100/3100-Avant Data Collection Softwaregeneric0Not reported
Thermo Fisher/ABI PRISM 310 Data Collection Softwaregeneric>=0 <=3.1Not reported
Thermo Fisher/ABI PRISM 310 Data Collection Softwaregeneric0Not reported
Thermo Fisher/Applied Biosystems 3130 Series Data Collection Softwaregeneric>=0 <=4.1Not reported
Thermo Fisher/Applied Biosystems 3130 Series Data Collection Softwaregeneric0Not reported
Thermo Fisher/Applied Biosystems 3500/3500xL Series Data Collection Softwaregeneric>=0 <=4.0.2Not reported
Thermo Fisher/Applied Biosystems 3500/3500xL Series Data Collection Softwaregeneric0Not reported
Thermo Fisher/Applied Biosystems 3730/3730xL Series Data Collection Softwaregeneric>=0 <=5.0.2Not reported
Thermo Fisher/Applied Biosystems 3730/3730xL Series Data Collection Softwaregeneric0Not reported
Thermo Fisher/Applied Biosystems GeneMapper ID-X Softwaregeneric>=0 <=1.7.3Not reported
Thermo Fisher/Applied Biosystems GeneMapper ID-X Softwaregeneric0Not reported
Thermo Fisher/Applied Biosystems SeqStudio Flex Series Instrument Softwaregeneric>=0 <=1.2.0Not reported
Thermo Fisher/Applied Biosystems SeqStudio Flex Series Instrument Softwaregeneric0Not reported
Thermo Fisher/Applied Biosystems SeqStudio Genetic Analyzer Data Collection Softwaregeneric>=0 <=1.2.5Not reported
Thermo Fisher/Applied Biosystems SeqStudio Genetic Analyzer Data Collection Softwaregeneric0Not reported

Recommended response

  1. 1Check inventory. Check lockfiles and deployed manifests for Thermo Fisher/ABI PRISM 3100/3100-Avant Data Collection Software, Thermo Fisher/ABI PRISM 3100/3100-Avant Data Collection Software, Thermo Fisher/ABI PRISM 310 Data Collection Software.
  2. 2Review the reported fix. Source-reported solution: Thermo Fisher has developed security updates to address the vulnerability. The security updates implement the use of digital signatures on the instrument software that adds an extralayer of protection. Moving forward, this will help users verify that data files have not been modified. Applied Biosystems 3500/3500xL Series Data Collection Software: Update to version 4.0.3 https://downloads.thermofisher.com/3500_DCS_v4.0.3_Patch/v4.0.3_Patch_Installer.exe Applied Biosystems 3730/3730xL Series Data Collection Software: Update to version 5.0.3 https://downloads.thermofisher.com/3730xl_UDC_v5.0.3_Patch/3730xl_UDC_v5.0.3_Patch.exe Applied Biosystems SeqStudio Genetic Analyzer Data Collection Software: Update to version 1.2.6 https://downloads.thermofisher.com/SeqStudio/1.2.6/SeqStudio-1.2.6.abpkg Applied Biosystems SeqStudio Flex Series Instrument Software: Update to version 1.2.1 https://downloads.thermofisher.com/SeqStudioFlex/1.2.1/SeqStudioFlex-1.2.1.abpkg Applied Biosystems GeneMapper ID-X Software: Update to version 1.7.4 https://downloads.thermofisher.com/GeneMapperID-Xv1.7.4_Patch/GMIDX_v1.7.4_Patch.exe

Evidence timeline and material changes

  1. Published upstream

    Aug 5, 2026

    Evidence: source:cvelist:source_dates:source-dates:record

  2. Source modified

    Aug 26, 2026

    Evidence: source:cvelist:source_dates:source-dates:record

  3. First seen by HOL

    Aug 5, 2026

Sources and claim methodology

  • Source referencedocuments.thermofisher.com
  • CISA Known Exploited Vulnerabilities catalogcisa.gov
  • Source referencecve.org
Upstream source description

The affected Thermo Fisher Applied Biosystems Genetic Analyzers are vulnerable because .fsa/.hid output files can be edited. An attacker could tamper with these files, altering DNA data and resulting in inaccurate DNA test outcomes.

Quoted source text, attributed separately from HOL analysis.