OpenSlide: openslide_read_region() returns uninitialized memory with libtiff 4.7.1 (CVE-2026-54604) | HOL Guard CVE

Unknown severity · Source severity not reportedCVE-2026-54604

OpenSlide: openslide_read_region() returns uninitialized memory with libtiff 4.7.1

Answer in brief

CVE-2026-54604 records a Unknown severity vulnerability in OpenSlide: openslide_read_region() returns uninitialized memory with libtiff 4.7.1. The current sources do not mark it as known exploited. The current feed maps openslide/openslide (generic). Check affected ranges and fixed versions before updating.

Analysis pending evidence review

HOL Guard separates source facts from reviewed analysis. See the methodology.

Published Sep 17, 2026Updated Sep 17, 2026Source checked Sep 17, 2026First seen by HOL Sep 17, 2026Material review Sep 17, 2026

Upstream Advisory

Key facts

Risk: Unknown severitySource severity not reported
Exploitation: Not marked as known exploited
Affected software: 1 mapped package or product
Fix availability: Not reported

Why this deserves its current priority

A CVSS score is not reported in the current record. The current sources do not mark it as known exploited. Treat this as a source-backed prioritization signal, not a statement about your environment.

Analysis status

Analysis pending evidence review

Factual feed record only; HOL analysis is not approved for indexing. Read the methodology.

Affected scope and exposure questions

The current feed maps openslide/openslide (generic). Check affected ranges and fixed versions before updating.

Mapped affected packages and fixed versions
Package	Affected range	Fixed version
openslide/openslidegeneric	< 4.0.1	Not reported

Recommended response

Check inventory. Check lockfiles and deployed manifests for openslide/openslide.
Review the reported fix. Monitor this advisory for an available fix and review any installs of the affected package.

Evidence timeline and material changes

Published upstream
Sep 17, 2026
Evidence: source:cvelist:source_dates:source-dates:record
Source modified
Sep 17, 2026
Evidence: source:cvelist:source_dates:source-dates:record
First seen by HOL
Sep 17, 2026

Sources and claim methodology

Upstream source description

OpenSlide is a C library for reading whole slide image files. Prior to 4.0.1, a behavior change in libtiff 4.7.1 causes the indirect TIFF tile path in src/openslide-decode-tiff.c and _openslide_tiff_read_tile() to request a full-height destination for a partial bottom tile row, allowing uninitialized heap memory to enter pixel data returned by openslide_read_region(). A crafted but valid slide can trigger the issue in TIFF-based formats other than Hamamatsu NDPI when a network service renders attacker-provided slides. Successful extraction depends on pixel transparency handling and recompression, OpenSlide with libtiff 4.7.0 or earlier is not affected, and official binary builds 4.0.0.10 and 4.0.0.11 are affected. This issue is fixed in OpenSlide 4.0.1 and official binary build 4.0.0.12.

Quoted source text, attributed separately from HOL analysis.